Cover art for podcast The Human Upgrade with Dave Asprey—formerly Bulletproof Radio

The Human Upgrade with Dave Asprey—formerly Bulletproof Radio

938 EpisodesProduced by Dave AspreyWebsite

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own pe… read more


Stabilize Your Blood Pressure Using Biofeedback – Mackay Rippey with Dave Asprey : 853

Let’s not sugarcoat it; both low blood pressure and high blood pressure are bad for you. With either, you can experience an inability to focus, dizziness, heart disease, and other health problems. You want to find a way to stabilize your blood pressure in the Goldilocks zone–just right.

Controlling blood pressure is especially important when it comes to heart disease, which is the leading cause of death for men, women, and people of most racial and ethnic groups in the United States. There used to be a significant gap between men and women in the incidence of heart disease, but that gap has closed over the past few decades and now women die of heart disease as frequently as men.

In this episode of Bulletproof Radio, I brought on an expert to talk about Zona Plus. Mackay Rippey serves on the Medical Advisory Board of Zona Health. He explains how the biofeedback device helps you train your own body to change your blood pressure, using isometric exercise. In this kind of muscle contraction, the muscle is tensed and working, but not actively shortening or lengthening. The Zona Plus looks like a joystick from a fighter airplane with a little digital screen on top. That screen gives you immediate feedback.

Let's jump right into some of the biochemistry that I found with Zona, Mackay says:

“I started with the hand grip. So, 30% is the magic Goldilocks percentage for your grip. So, you need to calculate what your grip strength is in the morning. It can vary from day to day and the optimal is 30%. Now, if you think you can calculate 30% just by knowing what you're feeling, you're sadly mistaken. That's why it helps to have a biofeedback device that tells you, "You're at 30%. Oh, and, by the way, you have to hold it for two minutes." So, if you think you can do that for two minutes, you need a feedback device. It just makes your life a lot easier.”

We discuss the effects of pre-hypertension and hypertension on your health, how to manage your blood pressure and how to keep your cardiovascular system functioning properly. We also get into nitric oxide, endothelial cells and red blood cells.

Eighty percent of Zona Plus users lower their blood pressure back to normal because Zona makes biofeedback so accessible. It leads to greater cognitive function, clears toxins from your body and more. Consider this hand-held device your cardio biohack. We also talk about the additional supplements you can take to pair with the Zona for faster and better results.

And for those of you who may think it’s too early in your life for Zona Plus, that you’ll use it when you’re older, Mackay says to remember this: “Now's the time to start ‘exercising,’ your endothelial cells so that they continue to function well as you increase your age so you're not only living longer, but you're living well as well.”

Mackay sees the impact of blood pressure across many areas of health:

  • He co-founded Beyond Protocols, an education accelerator for Functional Medicine practitioners. 
  • He formulates supplements for cardiovascular health that reduce blood pressure. 
  • He’s operated Mackay Rippey Acupuncture for more than 30 years. 
  • He hosts Lyme Ninja Radio, a podcast focused on the challenges and treatment of Lyme disease. 
  • And, he’s got a passion for nutrigenomic research.

Join us for this important conversation on heart disease, healthy hearts, the blood pressure rollercoaster and some key elements to creating a long healthy life.

Note for listeners: I previously interviewed Zona’s CEO, Mark Young. Learn more about Zona’s company history and how the device was developed in episode #601: Get a Grip on Your Blood Pressure

Enjoy! And get more resources at Dave.Asprey/podcasts.

Got a comment, idea or question for the podcast? Submit via this form.


Go to and use code DAVE2021 to save $150 off the Zona Plus.


Minerals for Cellular Health:, use code DAVE to get 20% off

Nature’s Nootropic:, use code DAVE15 for 15% off

Get Salty AF:, try the new watermelon and grapefruit flavors!




See Privacy Policy at and California Privacy Notice at

Educational emoji reaction


Interesting emoji reaction


Funny emoji reaction


Agree emoji reaction


Love emoji reaction


Wow emoji reaction


Are you the creator of this podcast?

Verify your account

and pick the featured episodes for your show.

Listen to The Human Upgrade with Dave Asprey—formerly Bulletproof Radio


A free podcast app for iPhone and Android

  • User-created playlists and collections
  • Download episodes while on WiFi to listen without using mobile data
  • Stream podcast episodes without waiting for a download
  • Queue episodes to create a personal continuous playlist
RadioPublic on iOS and Android
Or by RSS
RSS feed

Connect with listeners

Podcasters use the RadioPublic listener relationship platform to build lasting connections with fans

Yes, let's begin connecting
Browser window

Find new listeners

  • A dedicated website for your podcast
  • Web embed players designed to convert visitors to listeners in the RadioPublic apps for iPhone and Android
Clicking mouse cursor

Understand your audience

  • Capture listener activity with affinity scores
  • Measure your promotional campaigns and integrate with Google and Facebook analytics
Graph of increasing value

Engage your fanbase

  • Deliver timely Calls To Action, including email acquistion for your mailing list
  • Share exactly the right moment in an episode via text, email, and social media
Icon of cellphone with money

Make money

  • Tip and transfer funds directly to podcastsers
  • Earn money for qualified plays in the RadioPublic apps with Paid Listens