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Blood & Cancer

71 EpisodesProduced by MDedge Hematology OncologyWebsite

Interview-style hematology/oncology podcast from MDedge Hematology-Oncology. The show is hosted by Dr. David Henry with Pearls from Dr. Ilana Yurkiewicz for clinical hematology and oncology health care professionals. The information in this podcast is provided for informational and educational purpo… read more


Pancreatic cancer and clinical trials

Pancreatic cancer and clinical trials


David H. Henry, MD, host of Blood & Cancer, is on location at the 2019 annual meeting of the American Society of Clinical Oncology during this podcast, speaking with Davendra Sohal, MD, of the Cleveland Clinic. Dr. Sohal presented preliminary results from SWOG S1505, a phase 2 study on neoadjuvant chemotherapy for resectable pancreatic adenocarcinoma.

Plus, in Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about what happens when a cancer patient wants to act against medical advice.

Show Notes

By Emily Bryer, DO, resident in the department of internal medicine, University of Pennsylvania, Philadelphia

SWOG S1505 trial: Neoadjuvant chemotherapy experience with mFOLFIRINOX vs. gemcitabine/nab-paclitaxel for resectable pancreatic adenocarcinoma. 

  • Patients with resectable pancreatic adenocarcinoma typically have surgery prior to chemotherapy.
  • Many patients with pancreatic adenocarcinoma recur after surgery.
  • Randomized phase 2 trial of resectable pancreatic adenocarcinoma
    • Patients were given chemotherapy for 3 months. If there was no progression, patients underwent surgery, followed by more chemotherapy.
    • About one-third of these patients were found to have nonresectable disease.
    • Additional data will be published in 2020.
  • Neoadjuvant chemotherapy may be easier to tolerate since it is given prior to surgery.
  • Venous thromboembolism is a common among patients with metastatic pancreatic cancer.



SWOG S1505 trial: NCT02562716

ASCO 2019, Abstract 4137


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Interact with us on Twitter: @MDedgehemonc

David Henry on Twitter: @davidhenrymd

Ilana Yurkiewicz on Twitter: @ilanayurkiewicz


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