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Blood & Cancer

71 EpisodesProduced by MDedge Hematology OncologyWebsite

Interview-style hematology/oncology podcast from MDedge Hematology-Oncology. The show is hosted by Dr. David Henry with Pearls from Dr. Ilana Yurkiewicz for clinical hematology and oncology health care professionals. The information in this podcast is provided for informational and educational purpo… read more


Cancer trials in the community

Edward S. Kim, MD, of Levine Cancer Institute at Atrium Health in Charlotte, N.C., chats with David H. Henry, MD, host of Blood & Cancer, about how to perform clinical trials in the community oncology setting.

Plus, in Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, discusses a byproduct of our fragmented health care system – patients having to hear the same bad news repeated over and over.

Show notes 

  • Only 3%-4% of adult oncology patients are enrolled in clinical trials.
  • Most patients diagnosed with cancer are seen in community settings (as opposed to academic centers).
  • Oncologists in the community setting face significant obstacles to enrolling their patients in clinical trials:
    • Communication between academic and community centers often is lacking, especially in more rural areas of the country.
    • Community-based oncologists usually are not compensated for time spent on research or academic work.
    • Treatment pathways used by many oncologists may not offer any information regarding clinical trials.
    • The traditional infrastructure of a community practice may not have the necessary experts to facilitate clinical trial participation.
    • Community oncologists may not feel comfortable talking to their patients about a novel drug of which they have little knowledge.
  • How can community oncologists facilitate participation in clinical trials?
    • There must be a cultural change, starting with the organization’s leadership.
    • A study coordinator is crucial.
    • Data, finance, and regulatory individuals are likely required.
    • Coordination with pharmacy and pathology usually is necessary.
    • Electronically Accessible Pathways (EAPathways) is a tool developed by Dr. Kim’s team. It is available and allows any oncologist to input a patient’s information to determine if there is an appropriate clinical trial available.

Show notes by Sugandha Landy, MD, a resident in the department of internal medicine, University of Pennsylvania, Philadelphia

Dr. Kim can be reached at


Additional reading

Patronik KE and ES Kim. A novel clinical pathways approach to delivering regional-based clinical trials and patient care in a hybrid academic- community-based system. J Clin Pathways. 2018 May;4(4):52-5.

Ersek JL et al. Implementing precision medicine programs and clinical trials in the community-based oncology practice: Barriers and best practices. Am Soc Clin Oncol Educ Book. 2018 May 23:38:188-96.


For more MDedge Podcasts, go to

Email the show:

Interact with us on Twitter: @MDedgehemonc

David Henry on Twitter: @davidhenrymd

Ilana Yurkiewicz on Twitter: @ilanayurkiewicz


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