This audio program discusses the clinical case of a patient with both psychotic and obsessive-compulsive symptoms; the treatment of adolescent depression including 24-week outcomes of the TORDIA study; use of long-term fluoxetine versus lithium for relapse prevention in bipolar II disorder patients; the rationale and features of the Research Domain Criteria, a proposed framework for research on pathophysiology to inform future schemes for classification of mental disorders. Articles can be viewed online at www.ajp.psychiatryonline.org.
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