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American Journal of Psychiatry Audio

189 EpisodesProduced by American Journal of PsychiatryWebsite

Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings… read more


May 2020: Psychedelics and Psychedelic-Assisted Psychotherapy

Executive Editor Michael Roy speaks with Collin Reiff, M.D., and William McDonald, M.D., about their evidence-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders.

  • How hallucinogens were first used, and some of the key individuals involved in the development of these drugs for medical use [2:23]
  • What led to the worry about use of these compounds in the 1960s, and what actions did U.S. policymakers take at the time? [5:35]
  • How have opinions changed from the 1960s to the present? [7:01]
  • How the authors conducted their research [8:23]
  • How the authors determined which drugs to examine [9:38]
  • What findings stood out to the authors? [10:28]
  • Relationships between the psychological effects and the neurobiology of psychedelic compounds [12:59]
  • How ketamine came to be used in clinical care, and what studies have shown about its safety and effectiveness [14:18]
  • An outline of psycholytic therapy and psychedelic therapy [17:16]
  • What is the potential for these kinds of drugs to be misused? [19:24]
  • Conclusions that researchers, clinicians, and other mental health professionals should take away [21:15]
  • Recommendations for further research in this area [22:20]

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