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a16z Podcast

250 EpisodesProduced by Andreessen HorowitzWebsite

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon… read more

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TikTok & Beyond: The Algorithm Question, The Future of Product

September 20th, 2020


With the U.S. tech partnership for TikTok being finalized, what happens if source code is excluded (and more specifically, the For You Page …

The New Fan Club: Creators, Fans, and the Power of Markets (& Crypto)

September 18th, 2020


Today’s episode, part two in our two-part series on the Creator Economy, focuses on the new potential revenue streams and fan-engagement models …

So You Want to Launch a Newsletter: Tips From Writers

September 17th, 2020


This episode, part one in a two-part series on the Creator Economy, explores the process and economics behind creating an independent newsletter. In this candid conversation, host Lauren Murrow talks with four Substack …

Designing a Culture of Reinvention

September 15th, 2020


Since Netflix started in the late 90s as a DVD-by-mail rental service competing with Blockbuster, it has completely reinvented itself... twice – first, when it went from DVD rental to video streaming platform, and then …

Heroes & Myths in Entrepreneurship -- Guy Raz

September 12th, 2020


"I'm in a movie, but it's the wrong movie."

For better or for worse, we tell the story of entrepreneurs as one of the mythical hero's journey: that's …

The Question of Education

September 11th, 2020


Monopoly, oligopoly, cartel. All three of those words can describe the (not so) modern education system today, given the cost structures, economics, …

PPP and Fraud: Willful Deceit or Design Defect?

September 4th, 2020


This episode examines the potential for misuse and fraud among those applying for the Paycheck Protection Program (PPP)—and how fintech and software …

Measuring & Managing Community Orgs, Developer Relations and Beyond

August 30th, 2020


Okay, so we know community is important -- whether for developer relations for your product or other types of communities -- but how do we measure the success of community initiatives and even artifacts (like events or …

Reining in Complexity: Data Science & Future of AI/ML Businesses

August 21st, 2020


There is no spoon. Or rather, “There is no such thing as ‘data’, there’s just frozen models”, argues Peter Wang, the co-founder and CEO of Anaconda — who also created the PyData conferences and grew the early data …

Online Learning and the Ed Tech Debate

August 17th, 2020


This episode is all about education and technology, a topic that’s especially top of mind this week as students in much of the country return to …

On Vaccines and Vaccinology, in COVID and Beyond

August 14th, 2020


WHEN are we going to have a COVID-19 vaccine, and how the heck are we going from (what’s been traditionally been up to) 12 years or so of vaccine development compressed into 12 months or so? What will and won’t be …

Turning Open Source Developers Into Superfans

August 10th, 2020


In this episode, we continue our community series with a recent discussion that applies to many kinds of community building. Today’s topic: How do you create a platform that people not only use, but tell their friends …

Journal Club: Slaying the Sleeper Cells of Aging with CAR T

August 9th, 2020


CAR T therapy is a groundbreaking medicine that uses engineered T cells to attack cancer. But CAR T cells (that is, chimeric antigen receptor T cells) can be programmed to recognize a huge range of target proteins and …

Working, Making, Creating in Public... and Private

August 2nd, 2020


We're living in an unprecedented era of online collaboration, coordination, and creation. All kinds of people are coming together -- whether in an …

GPT-3: What's Hype, What's Real on the Latest in AI

July 30th, 2020


In this episode -- cross posted from our 16 Minutes show feed -- we cover all the buzz around GPT-3, the pre-trained machine learning model from OpenAI that’s optimized to do a variety of natural-language processing …

Taking the Pulse on Medical Device Security

July 22nd, 2020


Many don’t realize we even need to think about the possibility of security hacks when it comes to things like pacemakers, insulin pumps, and more. …

Journal Club: A New Path to Antibiotic Resistance

July 19th, 2020


Ever since the discovery of antibiotics, microbiologists have worried about and studied how bacteria acquire resistance to these drugs. Adding to the …

Cybercrime, Incorporated

July 18th, 2020


A dive into the sociological, operational, and tactical realities of this murky underworld, Lusthaus and de la Garza discuss who the players are, …

How Transparent Pricing Drives Healthcare Change

July 15th, 2020


Dr. Marty Makary—surgical oncologist at Johns Hopkins University School of Medicine, and health policy and innovation expert—has long been a …

Preserving Digital History: How to Close the Web's 'Memory Hole'

July 13th, 2020


More than 98% of the information on the web is lost within 20 years, and huge gaps exist in our digital and cultural history. Zoran Basich and Alex …

Alex Honnold on Human Performance (part 2) – Climbing and Entrepreneurship

July 11th, 2020


In part 1 of our series on human performance, we looked at the limits of human potential in climbing and other sports – and how we push those limits …

Alex Honnold on Human Performance (part 1) – Where's the Limit?

July 11th, 2020


Is there a limit to what humans can do? And if so, how do you know when you've reached it? Welcome to part one of a two-part series on human …

Why We Shouldn’t Fear AI in Healthcare

July 7th, 2020


"Why We Shouldn’t Fear the ‘Black Box’ of AI (in Healthcare and Everywhere)" by Vijay Pande. First published in the New York Times, January 2018. 

You …

When One App Rules Them All: The Case of WeChat and Mobile in China

July 7th, 2020


"When One App Rules Them All: The Case of WeChat and Mobile in China" by Connie Chan. First published August 2015. 

You can also find and share this …

Every Company Is a Fintech Company

July 7th, 2020


"Why Every Company Will Be a Fintech Company -- The Next Era of Financial Services and the 'AWS Phase' for Fintech" by Angela Strange.

You can also find and share this essay at



Read-Alouds, Continued

July 7th, 2020


Today we're continuing a series we started a while ago of read-alouds (for more context on the why and why now check out episode #500 on how we podcast!).

The first was episode #544 in April, It's Time to Build, read out …

Journal Club: Revisiting Eroom's Law

July 5th, 2020


Eroom’s Law is Moore’s Law spelled backwards. It’s a term that was coined in a Nature Reviews Drug Discovery article by researchers at Sanford Bernstein and describes the exponential decrease in biopharma research and …

Preventing Pandemics with Genomic Epidemiology

June 30th, 2020


The COVID-19 pandemic has increased the visibility of scientists and the scientific process to the broader public; suddenly, scientists working on …

Journal Club: Therapeutic Video Game on Trial

June 28th, 2020


In this episode of the a16z bio journal club, we cover one of the key clinical trials that supported the recent FDA approval of the first …

Gross Margins, Early to Late: What They Do (and Don't) Tell You

June 27th, 2020


Gross margins are essentially a company's revenue from products and services minus the costs to deliver those products and services to customers, and it's one of the most important financial metrics a startup can track.

Building Products for Power Users

June 24th, 2020


As more digital natives have entered the workplace, they have brought with them the expectation that their software should both be a joy to use and …

Journal Club: Building a Better Chloroplast

June 21st, 2020


In this episode of the a16z bio Journal Club, bio deal team partner Judy Savitskaya and Lauren Richardson discuss research that aims to enhance the efficiency of photosynthesis and carbon fixation. These two processes …

Real Estate in a Pandemic: Renters and Landlords (Part 2)

June 17th, 2020


This episode is the second in a two-part series that examines the pandemic’s impact on real estate. Part 1 focused on prospective home buyers, sellers, and existing homeowners. This episode, Part 2, addresses renters …

Real Estate in a Pandemic: Homeowners and Buyers (Part 1)

June 16th, 2020


This episode is the first in a two-part series that examines the pandemic’s impact on real estate. Part 1 focuses on prospective home buyers, sellers, and existing homeowners. Part 2 (streaming on 6/17) addresses …

World’s Largest Supercomputer v. Biology’s Toughest Problems

June 14th, 2020


Proteins are molecular machines that must first assemble themselves to function. But how does a protein, which is produced as a linear string of …

The Return of Home-based Healthcare

June 12th, 2020


The way we deliver healthcare has changed enormously over the last century, shifting from house calls by doctors to your own to institutionalized settings like hospitals and clinics. But now that trend has started to …

The Future of Primary Care

June 11th, 2020


Primary care was meant to be the front door to the healthcare system, but in some ways never set up for success to begin with. We need a new operating system for primary care—one with a different, deeper understanding …

All about Section 230: What It Does and Doesn't Say

June 9th, 2020


 We cover the tricky but important topic of Section 230 of the Communications Decency Act. The 1996 law has been in the headlines a lot recently, in the context of Twitter, the president’s tweets, and an executive order

What We Can't Reveal We Can't Heal

June 4th, 2020


Given recent events around George Floyd and far beyond, this special episode of the a16z Podcast features Shaka Senghor, a leading advocate for criminal justice reform (and bestselling author), and Terry Brown, a former …

SaaS Go-to-Upmarket

May 29th, 2020


For a SaaS company, it's easier to move upmarket than down, and this gives SaaS startups the advantage against incumbents. In this episode,  David Ulevitch and our newest enterprise general partner Kristina Shen look at …

New Fan Engagement Models for Athletes and Influencers

May 26th, 2020


Today’s episode is about a practical application of crypto — namely, the way it can “tokenize” fandom. More broadly, it’s about fan engagement, and …

Don't Call it a Brain in a Dish!

May 24th, 2020


Our understanding of the human brain and its disorders has always been limited by our lack of access to living, human, developing brain tissue. For the first time, that's changing. In this episode, Sergiu Pasca, …

Pandemics: Early Detection, Networks, Spreaders

May 23rd, 2020


Pandemics are predictable; what's not predictable is the intensity, or the precise timing of arrival. That's where early detection -- not just rapid warning (as with something like Google Flu Trends back in the day), or …

Podcasting and the Future of Audio

May 20th, 2020


This podcast (first recorded in 2019, now being rerun) -- is a podcast about podcasting: But it's really all about audio. A lot's changed... and a lot hasn't. 

How do we define "podcasts"; how does the feeds ecosystem …

Growth in Turbulent Times

May 15th, 2020


 In normal times, every company operates against some hypothetical growth model—a data-driven framework that describes how your product grows and how you acquire new users. These, of course, are not normal times. In the …

Journal Club: Using CRISPR to Prevent Coronavirus and Influenza Infection

May 15th, 2020


In this episode of a16z bio Journal Club, general partner Vijay Pande, bio deal team partner Andy Tran, and bio editor Lauren Richardson discuss a novel CRISPR-Cas-based anti-viral strategy.

The discussion covers the …

What's Next in Gaming

May 7th, 2020


Video game technology has evolved into a global phenomenon that extends far beyond entertainment. In this episode, John Riccitiello, CEO of the game …

Undruggable Drugs

May 6th, 2020


In this episode of the a16z Podcast, we take a deep dive into the world of drug development—specifically "undruggable drugs": a category of protein, …

The Next Generation of Cultural Influencers in Tech

May 2nd, 2020


This episode—which originally took place as a live event—is a conversation between Seattle Seahawks linebacker Bobby Wagner and a16z Cultural …

The Chief Security Officer in (and out of) a Crisis

April 29th, 2020


The Chief Security Officer (CSO/CISO) used to manage on-premise servers, now the information they have to secure has migrated to the cloud. As the …

Journal Club: Finding New Antibiotics with Machine Learning, What Coronavirus Structures Tell Us

April 26th, 2020


a16z Journal Club (part of the a16z Podcast), curates and covers recent advances from the scientific literature -- what papers we’re reading, and why …

Introducing Journal Club

April 26th, 2020


Announcing a16z Journal Club, a new show where we curate and discuss recent research papers with a16z experts and others. 

This new show continues the a16z Podcast mission of not just bringing you conversations about the …


April 21st, 2020


“It's Time to Build” by Marc Andreessen. 

You can also find and share this essay at

Introducing Read Alouds

April 21st, 2020


We wanted to let you know about a special new series of posts occasionally read out loud from us  (you can learn more about the why and why now in episode #500 on how we podcast); we may release these in a separate feed …

The Passion Economy: Redefining Work

April 18th, 2020


This episode of the a16z Podcast covers the the rise of online platforms that enable people to make a living off their unique interests and skills. It's a trend that's become increasingly relevant as the demand for …

When Bad Policy = Bad Business Models = Bad Public Health

April 16th, 2020


with @JorgeCondeBio, @julesyoo, and @omnivorousread

In some ways, the coronavirus feels like it came out of nowhere—a kind of Black Swan event. But at …

Moving to Remote Development (and Work)

April 15th, 2020


From agile project management to asynchronous collaboration, development teams have pioneered many of the tools and best practices for remote work. …

Virtual Oncology

April 10th, 2020


with @vintweeta @pbcancerdoc @sumitshahmd @omnivorousread

Coronavirus is now disrupting the entire health care system, not just because of the burden of dealing with the actual disease itself, but because of everything …

The Story of Schizophrenia

April 7th, 2020


Descriptions of the mental illness we today call schizophrenia are as old as humankind itself. And more than likely, we are are all familiar with …

Navigating the Numbers

April 4th, 2020


For any business, there are three core financial statements – the income or P&L statement, the balance sheet, and the cash flow statement. While these statements can show investors and the board how the business is …

Gaming and Livestreaming: Connecting While Distancing

April 2nd, 2020


Since social distancing measures were first put in place, time spent gaming has gone up—way up. According to a recent report by Verizon, video game usage in the U.S. has risen 75 percent during peak hours. The "stay at …

The Hustlers's Guide to Suing the Man

April 1st, 2020


This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for …

The Hustler's Guide to Elder Care

April 1st, 2020


This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for …

The Hustler's Guide to Nursing Jobs

March 30th, 2020


This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for …

Hustlin' Tech, Round Two

March 30th, 2020


This is the next cycle of Hustlin' Tech -- a podcast series co-hosted by bestselling authors, a16z co-founder Ben Horowitz; and Shaka Senghor, a leading voice in criminal justice reform.  

 Each episode is a "Hustler's …

Security When the Workforce Goes Remote

March 27th, 2020


We are in the midst of a rapid and unprecedented shift to remote work. What does it mean for security when the airgap between work and life is gone? …

The Delivery-Optimized Future of Food

March 25th, 2020


The spike in online ordering and food delivery—a trend that's particularly relevant now—is evidence of how tech is fundamentally changing how and …

When Medicine Goes Virtual

March 19th, 2020


We’re at a moment where we are now seeing medicine go virtual faster, and at a scale that it has never done before. In this conversation, …

Labs for Diagnostics: Then, Now, and Next

March 17th, 2020


A lot's going on in the world of healthcare right now, and one topic that's especially relevant is how diagnostic labs work. In this episode with Dave King, Executive Chairman of Lab Corp (one of the largest clinical …

How a16z's Crypto Startup School Went Remote

March 14th, 2020


On February 21, Andreessen Horowitz kicked off its very first Crypto Startup School, with 45 students from around the U.S. and three countries …

Drowning in Debt, Eager to Share: When Fintech Meets Social

March 12th, 2020


The last financial crisis prompted many consumers to reassess their banking expectations—none more so than millennials and Gen-Z-ers. While revealing one's financial information was once considered taboo, now consumers …

Innovation Through Software Development and IT

March 6th, 2020


One of the recurring themes we talk about a lot on the a16z Podcast is how software changes organizations, and vice versa... More broadly: it’s really about how companies of all kinds innovate with the org structures …

The Open Source CIO

February 28th, 2020


In 2014, in "Why There Will Never Be Another Red Hat," Peter Levine argued that Red Hat’s open source business model of commercializing support and …

Novel Coronavirus Updates: How Healthcare System, Tests Work; More

February 27th, 2020


This episode covers the following -- since our previous deep-dive on the novel coronavirus outbreak -- including:

  1. practical implications for the U.S. …

Metrics and Mindsets for Retention & Engagement

February 20th, 2020


It's "Marketplaces Week" for us at a16z, thanks to our consumer team releasing a new index of the next industry-defining marketplaces, the Marketplace 100.  

But what happens as such marketplaces and other platforms …

Tough Love, Global Diplomacy, and Lessons on Leadership

February 14th, 2020


Susan shares how she learned to leverage the characteristics of her personality early in her career as assistant secretary of state [2:05]

One of the important conversations Susan had with a mentor that changed the …

Building the First CAR T Company

February 7th, 2020


with @OzAzamTmunity1, @JorgeCondeBio, and @omnivorousread

CAR T therapy, the groundbreaking new medicines that uses engineered T-cells to attack cancer, has been so effective in childhood leukemias that we believe it may …

Rebel Talent

February 4th, 2020


When we think about rebellious behavior in the context of organizations and companies, we tend to think of rebels as trouble-makers, rabble-rousers; …

All about the Coronavirus

January 30th, 2020


This episode of 16 Minutes on the news from a16z is all about the recent coronavirus outbreak -- or rather, a new type of coronavirus called 2019-nCoV for 2019 novel coronavirus. Since it's an ongoing and …

The Truth about 1000 True Fans + Pricing Our Attention

January 27th, 2020


The idea of "1000 true fans" -- first proposed by Kevin Kelly in 2008 and later updated for Tools of Titans -- argued that to be a successful …

Writers Writing, Readers Reading, Creators Creating

January 27th, 2020


We've been financing good writing with bad advertising -- and "attention monsters" (to quote Craig Mod) for way too long. So what happens when the …

What's Next for the Internet?

January 19th, 2020


How can we evolve the web for a better future? Has the web become a mature platform — or are we still in the early days of knowing what it can do and …

Controlling AI

January 16th, 2020


AI can do a lot of specific tasks as well as, or even better than, humans can — for example, it can more accurately classify images, more efficiently …

Food, Drugs, and Tech—100 Years of Public Health

January 14th, 2020


The federal agency known as the FDA, or the Food and Drug Administration, was born over 100 years ago—at the turn of the industrial revolution, in a …

On Pharma Trends and Big Company Innovation

January 11th, 2020


How does the world’s largest producer of medicines in terms of volume balance the science and the business of innovation? How does an enterprise at …

Personal Genomics: Where Are We, Really?

January 6th, 2020


This is a turn of the decade (and January-themed) look backward/ look forward into personal genomics, given recent and past retrospective and prospective pieces in the media on the promise, and perils, of the ability to …

Why We Should Be Optimistic About the Future

January 2nd, 2020


Many skeptics thought the internet would never reach mass adoption, but today it’s shaping global culture, is integral to our lives -- and it's just …

What to Know about CFIUS

December 23rd, 2019


When innovation and capital go global, so do restrictions on trade, foreign investment, and more. Over the past couple years, U.S. policymakers have

Are ISAs the Solution to Student Debt?

December 19th, 2019


A bold proposal: You go to college for free, then pay back the school after graduation—but only if you get a job in your field of study and make a …

Shonda Rhimes on How to Create Stories (and Products) People Want

December 17th, 2019


Hollywood and Silicon Valley seem so different, but are more alike than we think. What challenges do tech startup founders and other creative …

The Journey from 0 to 1, from Mosaic to Netscape

December 17th, 2019


As part of a new series where we will share select a16z partner appearances on other podcasts with our audience here, this episode is cross-posted from the new show Starting Greatness -- featuring interviews with …

Direct Listings, Myths and Facts

December 11th, 2019


We’ve covered a lot of the strategic financing milestones for startups seeking to build a sustainable and enduring business -- from mindsets for startup fundraising to when and how to build a finance functionwith a CFO

The Stories and Code of Culture Change

December 7th, 2019


There are some common tropes that can kill your company culture -- whether it's that corporate values can be weaponized; "fake it til you make it"; …

Of Container Ships, Supply Chains, and Retail

December 3rd, 2019


This podcast rerun -- first recorded over two and a half years ago, now being rerun as one of our evergreen classics on the tails of the world's largest designated shopping days (Black Friday, Singles Day in China, …

Nursing Today, From the Bedside and Beyond

November 28th, 2019


"Constant attention by a good nurse may be just as important as a major operation by a surgeon”, diplomat Dag Hammarskjöld once observed -- and that may be more true today than ever before. For most of us, nurses are …

How We Podcast

November 27th, 2019


"Hi everyone, welcome to the a16z Podcast..." ... and welcome to our 500th episode, where, for the first time, we reveal behind-the-scenes details and the backstory of how we built this show, and the broader editorial …

Brand Building Ideas… and People

November 20th, 2019


Many technical founders, academics, and other experts often believe that great products -- or great ideas! -- sell themselves, without any extra effort or marketing. But in reality, they often need PR (public relations).

Come for the Games, Stay for the Party

November 2nd, 2019


The games industry is in the midst of a tectonic shift. Powered by platform convergence, games-as-a-service, and user-generated content, modern video …

AI in B2B

October 24th, 2019


Consumer software may have adopted and incorporated AI ahead of enterprise software, where the data is more proprietary, and the market is a few thousand companies not hundreds of millions of smartphone users. But …

Free Software and Open Source Business

October 21st, 2019


Today, despite the critical importance of open source to software, it’s still seen by some as blasphemous to make money as an open source business. In this podcast, Armon Dadgar, Cofounder and CTO of HashiCorp; Ali …

Of Emojis and Innovation

October 15th, 2019


This rerun podcast (first recorded in 2015, now being rerun as one of our evergreen classics/ favorites) -- is ALL about emoji. But it's really about how innovation really comes about: through the tension between open …

The Environment, Capitalism, Technology

October 4th, 2019


It used to be that the only way for humanity to grow -- and progress -- was through destroying the environment. Sure, the Industrial Revolution …

16 Minutes on the News #10: Amazon Healthcare, Oculus VR/AR, Google Quantum Supremacy?

September 30th, 2019


Our news podcast, 16 Minutes -- where we quickly cover the top headlines of the week, the a16z way (why are these topics in the news; what's real, what's hype from our vantage point of tech trends) -- is now only

New Business Models for Gaming, Collaboration, Creativity

September 28th, 2019


The combination of cloud, social, and mobile took gaming beyond a small base of just console- and PC-gamers to a massive player base. But the …

16 Minutes on the News #9: All the Recent Phone Hacks

September 23rd, 2019


This is episode #9 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they’re in the news; why they matter from our vantage point in tech -- and share our experts’ …

a16z Podcast: The Biology of Pain

September 17th, 2019


What is the nature of physical pain? Why do we even experience it? Is there one type, or many? Do people experience pain differently? What is happening in our brains and our bodies when we experience pain? What is the …

16 Minutes on the News #8: Apple Camera, Services; Wearables - Where are We

September 16th, 2019


with @benedictevans @vijaypande and @smc90

This is episode #8 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage …

a16z Podcast: How to Pay for Healthcare Based on Health

September 6th, 2019


There's been a lot of talk about the need for our healthcare system to shift away from volume and fee-for-service, where you pay by appointment, …

The Hustler's Guide to the Hair Business

September 6th, 2019


with @bhorowitz @shakasenghor @diishanimira @therealritabee

Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology …

The Hustler's Guide to Getting Paid

September 6th, 2019


with @bhorowitz @shakasenghor ram @earnin & vaughn ferguson

Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology …

The Hustler's Guide to Preschool

September 6th, 2019


with @bhorowitz @shakasenghor @8ennett & sherie james

Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology …

Introducing Hustlin' Tech

September 6th, 2019


We're excited to introduce a new podcast series hosted by a16z co-founder Ben Horowitz and Shaka Senghor, a leading voice in criminal justice reform and bestselling author. The series is called “Hustlin’ Tech” and so …

a16z Podcast: Making Culture, Making Influence -- Dapper Dan!

September 2nd, 2019


"You cannot be IN it... and not be OF it."

Dapper Dan a.k.a. Daniel Day shares his remarkable history and story of defining an era of fashion and …

a16z Podcast: From the Internet's Past to the Future of Crypto

August 29th, 2019


What can we learn from the history of the internet for the future of crypto? In this episode of the a16z Podcast, general partner Katie Haun interviews a16z co-founder Marc Andreessen -- and co-founder of Netscape, …

a16z Podcast: What to Know about FedRAMP

August 28th, 2019


with @ldhawke and @stevesi

The government wants to get onto the cloud! But how do they assess the levels of risk in adopting specific cloud products, and which "cloud service providers" (aka "CSPs") to work with? That's …

16 Minutes on the News #7: Apple Card, BEC Scams Federal Indictment

August 25th, 2019


with @illscience and @smc90

This is episode #7 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech …

a16z Podcast: Software has eaten the world...and healthcare is next

August 15th, 2019


Back in 2011, a16z cofounder Marc Andreessen first made the bold claim that software would eat the world. In this episode (originally recorded as …

16 Minutes on the News #6: Health Claims, Corporate Breaches

August 12th, 2019


with @julesyoo @smc90

This is episode #6 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why …

16 Minutes on the News #5: Fed Real-time Payments, Death of Retail

August 11th, 2019


with @astrange @jeff_jordan and @smc90

This is episode #5 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point …

16 Minutes on the News: The Opioid Crisis

August 4th, 2019


with @jorgecondebio @vijaypande and @smc90

This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage …

16 Minutes on the News: Fortnite, Esports, Gaming, and Entertainment

August 4th, 2019


with @andrewchen @dcoolican and @smc90

This is episode #3 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z …

16 Minutes on the News: Mobile Malware, Drug Pricing

July 28th, 2019


with @martin_casado @jorgeconde @jayrughani and @smc90

This is episode #2 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from …

a16z Podcast: The Search for the Secret Metal that Powers All Our Devices

July 23rd, 2019


with Kurt House (@kurtzhouse), John Thompson, Connie Chan (@conniechan) and Hanne Tidnam (@omnivorousread)

The exploration for and mining of certain metals has driven huge epochs of human civilization, from copper and …

16 Minutes on the News: Neuralink & Brain Interfaces, TikTok, FaceApp, iHeartRadio

July 21st, 2019


with @vijaypande @conniechan @jpm25 and @smc90

Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's …

a16z Podcast: How To Get The Most From Your Board

July 19th, 2019


In this final of a 3-part series (which originally aired as YouTube videos) on working with venture investors, a16z Managing Partner Scott Kupor shares best practices for working with your board as it grows from just …

a16z Podcast: How To Raise Money From A Venture Investor

July 18th, 2019


So you've decided raising venture capital is the best fundraising strategy for your startup. Now what?

In this second of a 3-part series, a16z Managing Partner Scott Kupor shares actionable fundraising advice based on …

a16z Podcast: How To Understand And Choose A Venture Investor

July 17th, 2019


Incentives matter. So understanding the incentives of venture capitalists will help you decide if raising money from a venture investor makes sense for your business.

In this first of a 3-part series, which originally …

a16z Podcast: Beyond Software, to Talent and Culture

July 4th, 2019


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen)

Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our …

a16z Podcast: Beyond Zero Sum, Again

July 4th, 2019


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson)

Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of …

a16z Podcast: Beyond Software Eating the World

July 4th, 2019


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), Scott Kupor (@skupor), and Sonal Chokshi (@smc90)

Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re …

a16z Podcast: Beyond Disruption Theory

July 4th, 2019


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Michael Copeland

Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous …

a16z Podcast: Entrepreneurs, Then and Now

June 28th, 2019


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Stewart Butterfield (@stewart)

A lot in technology -- and venture -- happens in …

a16z Podcast: Damage-free Genome Editing -- Next in CRISPR

June 26th, 2019


Two recent scientific journal papers show what's possible when CRISPR moves from cutting DNA tool to a full-fledged platform -- expanding its toolkit …

a16z Podcast: Stories from the Frontlines of Synthetic Fraud

June 25th, 2019


Synthetic fraud—yes, it's a thing: a new evolution of consumer fraud that’s been emerging in financial services, to the tune of $1-$2B a year.

In …

a16z Podcast: The History and Future of Machine Learning

June 19th, 2019


How have we gotten to where were are with machine learning? Where are we going?

a16z Operating Partner Frank Chen and Carnegie Mellon professor Tom …

a16z Podcast: The Politics of Technology

June 15th, 2019


with Tony Blair (@InstituteGC), Scott Kupor (@skupor), and Sonal Chokshi (@smc90)

If the current pace of tech change is the 21st-century equivalent …

a16z Podcast: AI and Your Doctor, Today and Tomorrow

June 13th, 2019


with Eric Topol (@EricTopol) and Vijay Pande (@vijaypande)

Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol, …

a16z Podcast: 10+1 Lessons from Serial Entrepreneur Justin Kan

June 10th, 2019


Want actionable advice from a founder who has built multiple tech companies and has invested the time to be open, introspective, and transparent …

a16z Podcast: Deep Learning for the Life Sciences

June 6th, 2019


with Vijay Pande (@vijaypande) and Bharath Ramsundar

Deep learning has arrived in the life sciences: every week, it seems, a new published study comes out... with code on top. In this episode, a16z General Partner Vijay …

a16z Podcast: The Power of Restorative Justice

June 3rd, 2019


with Van Jones (@VanJones68), Shaka Senghor (@ShakaSeghnor), and Chris Lyons (@clyons)

True redemption can be hard to come by in our justice system today. And yet, we need it more than ever before. In this episode …

a16z Podcast: The Economics of Expensive Medicines

May 30th, 2019


with Andrew Lo (@AndrewWLo) and Jorge Conde (@JorgeCondeBio)

The advent of new gene and cell therapies are beginning to approach that holy grail of …

a16z Podcast: Collectively Driving Change

May 27th, 2019


with Laurene Powell Jobs (@LaurenePowell) and Ben Horowitz (@bhorowitz)

Laurene Powell Jobs is, among many other things, founder and President of the …

a16z Podcast: What Time Is It? From Technical to Product to Sales CEO

May 20th, 2019


with David Ulevitch (@davidu) and Sonal Chokshi (@smc90)

Since the startup (and founder) journey doesn't go neatly linear from technical to product to sales, tightening one knob (whether engineering or marketing or …

a16z Podcast: Five Open Problems Toward Building a Blockchain Computer

May 13th, 2019


Do you sometimes wish you had been born in a different decade so you could have worked on the fundamental building blocks of modern computing? How …

a16z Podcast: A Guide to Making Data-Based Decisions in Health, Parenting... and Life

May 11th, 2019


with Emily Oster (@ProfEmilyOster) and Hanne Tidnam (@omnivorousread)

Are chia seeds actually that good for you? Will Vitamin E keep you healthy? Will breastfeeding babies make them smarter? There’s maybe no other arena …

a16z Podcast: Innovating in Bets

May 8th, 2019


with @annieduke, @pmarca, and @smc90

Every organization, whether small or big, early or late stage -- and every individual, whether for themselves or others -- makes countless decisions every day, under conditions of …

a16z Podcast: Seven Trends in Blockchain Computing

May 7th, 2019


In a followup to one of our most popular podcast episodes which originally aired in April 2017 (

a16z Podcast: The Future Of Decision-Making—3 Startup Opportunities

April 29th, 2019


As companies digitize, they change the way they make decisions: decisions are made lower in the organization, based on data, and increasingly automated. This creates opportunities for startups creating new ways to …

a16z Podcast: So You Wanna Build a Software Company in Healthcare?

April 25th, 2019


with Jorge Conde (@JorgeCondeBio), Julie Yoo (@julesyoo), and Hanne Tidnam (@omnivorousread)

Building a software company in healthcare is hard -- and …

a16z Podcast: Inside Apple Software Design

April 19th, 2019


Join longtime Apple software engineer Ken Kocienda in conversation with a16z Deal and Research operating partner Frank Chen for an insider’s account …

a16z Podcast: Fintech for Startups and Incumbents

April 4th, 2019


In this episode of the a16z Podcast -- which originally aired as a video on YouTube -- general partner Alex Rampell (and former fintech entrepreneur as the CEO and co-founder of TrialPay) talks with operating partner …

a16z Podcast: A Podcast About Podcasting

April 3rd, 2019


with Nick Quah (@nwquah), Connie Chan (@conniechan), and Sonal Chokshi (@smc90)

It's a podcast about podcasting! About the state of the industry, that is. Because a lot has changed since we recorded "a podcast about …

a16z Podcast: How Many Taps in the Apple (Plus) Tree?

March 30th, 2019


with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi)

What does Apple's recent event — in which a range of new services was announced, from Apple News Plus to Apple TV Plus to the Apple card — mean for the …

a16z Podcast: Incenting Innovation Inside, Loonshots to Moonshots

March 25th, 2019


with Safi Bahcall (@safibahcall), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)

A "moonshot" is a destination (like going to the moon, quite …

a16z Podcast: For the Billions of Creatives Out There

March 16th, 2019


with Brian Koppelman (@briankoppelman), Marc Andreessen (@pmarca), and Sonal Chokshi (@smc90)

The writer-showrunner is a relatively new phenomenon in TV, as opposed to film, which is still a director-driven enterprise. …

a16z Podcast: Lessons Learned from Chinese Education Startups

March 12th, 2019


When people talk about trends in education technology, they often focus on how to disrupt higher education in the U.S., whether it's about breaking …

a16z Podcast: What's in the Water at the George Church Lab?

February 26th, 2019


with George Church (@geochurch) and Jorge Conde (@JorgeCondeBio)

Renowned scientist George Church is known for his groundbreaking work and methods used for the first genome sequence, and for his work in genome editing, …

a16z Podcast: Capitalizing on an Autonomous Vehicle Future

February 24th, 2019


with Peter Ludwig, Qasar Younis (@qasar), and Sonal Chokshi (@smc90)

When people talk about autonomous vehicles, we hear everything from "we're much closer than you think" to "we're much further than you think". So …

a16z Podcast: Gaming Goes Mainstream

February 17th, 2019


Bobby Kotick is the CEO of Activision Blizzard (a merger he engineered); it's one of only two video gaming companies in the Fortune 500, and the largest game network in the world. The company is responsible for some of …

a16z Podcast: Who's Down with CPG, DTC? (And Micro-Brands Too?)

February 16th, 2019


with Ryan Caldbeck (@ryan_caldbeck), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90)

It's clear that all kinds of commerce companies and consumer products have been disrupted -- or enabled -- by tech. Yet for …

a16z Podcast: To All the Robots I've Loved Before

February 14th, 2019


with Kate Darling (@grok_) and Hanne Tidnam (@omnivorousread)

We already know that we have an innate tendency to anthropomorphize robots. But beyond just projecting human qualities onto them, as we begin to share more …

a16z Podcast: Cryptonetworks as Emerging Economies (Done Right?)

February 12th, 2019


with Chris Burniske (@cburniske), Joel Monegro (@jmonegro), Denis Nazarov (@Iiterature), and Jesse Walden (@jessewldn)

When designing cryptonetworks -- really, emerging economies -- how do we avoid some of the monetary …

a16z Podcast: Voting, Security, and Governance in Blockchains and Cryptonetworks

February 10th, 2019


with Phil Daian (@phildaian) and Ali Yahya (@ali01)

Whether in corporations, boardrooms, or political elections, voting is something we see in all …

a16z Podcast: Product-Market SALES Fit (What Comes First?)

February 3rd, 2019


with Jyoti Bansal (@jyotibansalsf), Peter Levine, Satish Talluri (@satishtalluri), and Sonal Chokshi (@smc90)

One of the toughest challenges for founders -- and especially technical founders who are used to focusing so …

a16z Podcast: Stories and Lessons in Enterprise Sales

January 30th, 2019


with Mark Leslie (@mleslie45) and Peter Levine

What does it actually take to win at enterprise sales? In this episode, Mark Leslie, former CEO and chairman and founding team member of Veritas Software, and a lecturer at …

a16z Podcast: Finding Go-to-Market Fit in the Enterprise

January 30th, 2019


with Peter Levine, Bob Tinker, and Hanne Tidnam (@omnivorousread)

For consumer companies, often when the holy grail of product-market fit is …

a16z Podcast: Connecting Hearts, Bodies, and Networks to Cure Cancer

January 26th, 2019


Veterinary oncology can inform human oncology, and vice versa -- providing a better model for looking at drug performance, interrelationships, and …

a16z Podcast: The Business of Cybercrime

January 17th, 2019


with Joel de la Garza, Jonathan Lusthaus, and Hanne Tidnam (@omnivorousread)

The idea of the cybercriminal as lone wolf or hobby hacker is no longer …

a16z Podcast: Pulse Check on Consumer Tech Trends 2019, CES and Beyond

January 17th, 2019


with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi)

Every year, the Consumer Electronics Show (CES) puts the latest and greatest …

a16z Podcast: Dark Data in Healthcare

January 16th, 2019


with Susannah Fox (@susannahfox), Anil Sethi (@anilsethiusa / @ciitizencorp), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)

The problem of "dark data" in healthcare isn't just a feel-good empowerment thing, but …

a16z Podcast: The Science and Business of Innovative Medicines

January 14th, 2019


with Vas Narasimhan (@vasnarasimhan), Jorge Conde (@jorgecondebio), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)

On average, only 1 out of 20 medicines works when we actually bring them into the human body, and …

a16z Podcast: All About Synthetic Biology

January 11th, 2019


with James J. Collins, Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread)

The idea of 'designing biology' -- once science fiction -- has …

a16z Podcast: What’s Next for Marketplace Startups (Hint: Services)

January 9th, 2019


The past and future of marketplace startups -- where are we? Ever since eBay popularized an internet meeting place for buyers and sellers of, well, …

a16z Podcast: Talent, Tech Trends, and Culture -- with Ben, Marc, and Tyler Cowen

December 29th, 2018


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen)

This episode of the a16z Podcast features the rare combination of a16z co-founders Marc Andreessen and Ben Horowitz in …

a16z Podcast: How the Internet Happened

December 24th, 2018


In his book (and podcast), Brian McCullough chronicles the history and evolution of the internet -- from college kids in a basement and the dot-com …

a16z Podcast: All About Stablecoins

December 21st, 2018


with Andy Milenius (@realzandy), Jesse Walden (@jessewldn), and Sonal Chokshi (@smc90)

The history, evolution, and use of money revolves around the …

a16z Podcast: The Infrastructure of Total Health

December 21st, 2018


with Bernard J. Tyson (@bernardjtyson) and Ben Horowitz (@bhorowitz)

Bernard J. Tyson is the chairman and CEO of Kaiser Permanente, a $73 billion non-profit health organization that provides healthcare and coverage with …

a16z Podcast: Building Crypto, from Vision to Reality

December 18th, 2018


with Brian Armstrong (@brian_armstrong), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90)

Where are we, really, right now -- in terms of what we can/ can't do with crypto today? And what will it take to get from vision …

a16z Podcast: On Marrying Entertainment and Technology

December 5th, 2018


with Jeffrey Katzenberg, Meg Whitman (@MegWhitman), and Marc Andreessen (@pmarca)

In this episode of the a16z Podcast, based on a discussion that took place at our annual a16z Summit, Marc Andreessen interviews Jeffrey …

a16z Podcast: The IQ and EQ of Robots

November 21st, 2018


with Boris Sofman (@bsofman), Dave Touretzky (@DaveTouretzky), and Hanne Tidnam (@omnivorousread)

We're just now beginning to truly see the the first …

a16z Podcast: Ancient Dreams of Technology, Gods & Robots

November 19th, 2018


with Adrienne Mayor (@amayor) and Hanne Tidnam (@omnivorousread)

Is it possible that ancient Greeks and Romans dreamed of technological innovations …

a16z Podcast: M&A and Innovation, Inside Out

November 17th, 2018


with Stephanie Cohen and Martin Casado (@martin_casado)

As chief strategy officer of Goldman Sachs (and former global head of financial sponsors …

a16z Podcast: Automation + Work, Human + Machine

November 5th, 2018


with Prasad Akella, Paul Daughtery (@pauldaugh) and Frank Chen (@withfries2)

What is different on that factory floor from Henry Ford to today? In …

a16z Podcast: Eyeballs on the Game

October 19th, 2018


with Jeff Jordan (@Jeff_Jordan), Yogi Roth (@YogiRoth), Zack Weiner and Hanne Tidnam (@omnivorousread)

For decades, the increasing value of sports teams, rights, licenses and more have been fueled by sports media. But …

a16z Podcast: From Research to Startup, There and Back Again

October 8th, 2018


The period from 2000-2016 was one of the best of times and worst of times for tech and the Valley (dotcom, financial crisis, Google IPO, Facebook founded, unprecedented growth, and so on), and John Hennessy -- current …

a16z Podcast: How to Manage a PR Agency

September 27th, 2018


with Shannon (Stubo) Brayton (@sstubo), Margit Wennmachers (@wennmachers), and Sonal Chokshi (@smc90)

One of the company building topics that’s surprisingly mystifying is PR -- and only surprising since so much of the …

a16z Podcast: New Upstarts in an Old Industry

September 25th, 2018


with Michael Ovitz (@michaelovitz), Ben Horowitz (@bhorowitz), and Hanne Tidnam (@omnivorousread)

When Michael Ovitz co-founded the Hollywood talent …

a16z Podcast: Technological Trends, Capital, and Internet 'Disruption'

September 24th, 2018


with Fred Wilson (@fredwilson) and Chris Dixon (@cdixon)

There's all sorts of interesting tech trends happening right now, including AI, VR/AR, self-driving cars and drones (as well as interesting stuff happening in …

a16z Podcast: Tesla and the Nature of Disruption

September 17th, 2018


with Benedict Evans (@BenedictEvans) and Steven Sinofsky (@SteveSi)

In another of our hallway conversation episodes, Benedict Evans and Steven Sinofsky talk all about Tesla — and more broadly, the nature of disruption …

a16z Podcast: What's at the Core of the Latest Apple Announcement?

September 14th, 2018


with Benedict Evans (@BenedictEvans) and Steven Sinofksy (@StevenSi)

In this hallway-style conversation episode of the a16z Podcast, Benedict Evans and a16z board partner Steven Sinofsky discuss Apple’s September 2018 …

a16z Podcast: Seeing into the Future -- Making Decisions, Telling Stories

September 8th, 2018


with Steven Johnson (@stevenbjohnson), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90)

There's a lot of research and writing out there on "thinking fast" -- the short-term, gut, instinctual decisions we make, biases …

a16z Podcast: The Case Study of Dollar General and Surviving (Thriving!) Retail

September 4th, 2018


with Jeff Jordan (@Jeff_Jordan), Cal Turner Jr., and Hanne Tidnam (@omnivorousread)

The "death of retail" in the face of e-commerce and tech disruption is a very real phenomenon, but what about the flip side of that …

a16z Podcast: When Organic Growth Goes Enterprise

August 25th, 2018


with Martin Casado (@martin_casado), Andrew Chen (@andrewchen), Russ Heddleston (@rheddleston), and Hanne Tidnam (@omnivorousread)

What happens when the bottoms up, organic growth usually associated with consumer …

a16z Podcast: Crypto and the Evolution of Open Source

August 20th, 2018


with Devon Zuegel (@devonzuegel), Denis Nazarov (@iiterature), and Jesse Walden (@jessewldn)

The open source movement enabled so much in computing, …

a16z Podcast: The Basics of Growth 2 -- Engagement & Retention

August 9th, 2018


with Andrew Chen (@andrewchen), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90)

Once you have users, how do you keep them engaged, retain them, and even "resurrect" or re-engage them? That's the focus of this …

a16z Podcast: The Basics of Growth 1 -- User Acquisition

August 9th, 2018


with Andrew Chen (@andrewchen), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90)

Growth is one of the most top of mind questions for entrepreneurs building startups of all kinds (and especially consumer ones) -- …

a16z Podcast: Earned Secrets

August 3rd, 2018


with Ben Horowitz (@bhorowitz) and Sharon Chang (@sychang)

What does it really take to start a startup (or work at one)? In this episode of the a16z Podcast -- based on a Q&A with Ben Horowitz as part of an event …

a16z Podcast: Cryptonetworks and Cities -- Analogies

August 1st, 2018


with Denis Nazarov (@iiterature), Jesse Walden (@jessewldn), Ali Yahya (@ali01), and Devon Zuegel (@devonzuegel)

Cryptonetworks are often compared to firms, people, or even coral reefs -- but, observes a16z crypto …

a16z Podcast: Cryptonetworks and Decentralization -- Building Blocks

August 1st, 2018


with Chris Dixon (@cdixon), Ali Yahya (@ali01), and Devon Zuegel (@devonzuegel)

“Show me the incentive and I'll show you the outcomes.”

At the end of the day, observes a16z crypto general partner Chris Dixon, Satoshi's …

a16z Podcast: High Growth in Companies (and Tech)

July 20th, 2018


with Elad Gil (@eladgil) and Chris Dixon (@cdixon)

There's a lot of knowledge out there -- and networks of talent (especially in Silicon Valley) -- on what to do in the early stages of a company, going from 0 to 1, and …

a16z Podcast: The Regulatory Landscape for Crypto

July 17th, 2018


with Katie Haun (@katie_haun), Robin Weisnman (@robinweisman), and Sonal Chokshi (@smc90)

What’s going on, regulation-wise, in crypto? How should …

a16z Podcast: Building Companies in Crypto, from People to Code

July 17th, 2018


with Tina Bhatnagar (@tinab), Preethi Kasireddy (@iam_preethi), Lily Liu (@calilyliu), and Kim Milosevich (@kimbatronic)

Whether it’s sharing the decision-making behind joining a crypto company to the perspectives of a …

a16z Podcast: Decentralization and Crypto, the Big Picture

July 16th, 2018


with Chris Dixon (@cdixon), Elizabeth Stark (@starkness), and Jessica Verrilli (@jess)

Why does decentralization matter? This episode of the a16z Podcast -- based on a discussion that first took as part of an “Intro to …

a16z Podcast: The Scientific Revolution of Ancient DNA

July 13th, 2018


with Jorge Conde (@jorgecondebio), David Reich, and Hanne Tidnam (@omnivorousread)

Trying to reconstruct the deep past of ancient humans out of present-day people has until now been like trying to reconstruct a bomb …

a16z Podcast: On Mentors and Mentees

July 12th, 2018


with Ken Coleman, Ben Horowitz (@bhorowitz), and Michel Feaster (@michelfeaster)

Everyone talks about the importance of mentorship in our …

a16z Podcast: Beyond Zero-Sum Thinking in the Game of Tech... and Life

July 6th, 2018


with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson)

The rise of zero-sum thinking -- which has come snapping back recently -- slows and even halts progress, observes Marc …

a16z Podcast: All Things Compensation

June 21st, 2018


Compensation is a topic near and dear to everyone’s heart… but what does “compensation” fully mean — and what does it include, what doesn’t it …

a16z Podcast: Construction Under Tech -- The Build

June 14th, 2018


with Martin Fischer (@fischermartin), Saurabh Ladha (@ladhasaurabh), Chris Rippingham, and Hanne Tidnam (@omnivorousread)

Continuing our series on how tech is changing construction -- one of the industries most …

a16z Podcast: Construction Under Tech -- Info Flows

June 13th, 2018


with Greg Lynn (@greglynnform), Gina Neff (@ginasue), Tracy Young (@Tracy_Young), and Hanne Tidnam (@omnivorousread)

Construction has been one of the industries most resistant to innovation and change over the last …

a16z Podcast: The End (and Beginning) of Programming

June 8th, 2018


There are over 20 million programmers out there -- and double that, if you count everyone else coding in other ways -- but where are the next 100 million developers? How do we get to a billion developers? The answer, …

a16z Podcast: The Hard Things about Security

June 6th, 2018


Here's the hard thing about security: the more authentication factors you have, the more secure things are... but in practice, people won't use too many factors, because they want ease of use. There's clearly a tension …

a16z Podcast: Autonomy in Service

May 25th, 2018


with Gregory Allen (@Gregory_C_Allen), Gayle Lemmon (@gaylelemmon), Ryan Tseng, and Hanne Tidnam (@omnivorousread)

We now live in a world where connecting the dots between intel and modeling threats has become …

a16z Podcast: When Journalism Goes Global

May 23rd, 2018


The International Consortium of Investigative Journalists is the organization responsible for the compilation and release of the first the Panama Papers, a series of 11.5 million documents that detailed the offshore …

a16z Podcast: B2B2C

May 18th, 2018


When it comes to B2B2C business models -- which combine both business to business (B2B) and business to consumer (B2C) -- who really "owns" the customer? That question might not matter as much in more symbiotic, …

a16z Podcast: Network Effects, Origin Stories, and the Evolution of Tech

May 17th, 2018


“The rules of the game are different in tech,” argues — and has long argued, despite his views not being accepted at first — W. Brian Arthur, …

a16z Podcast: The Oral History Of TrialPay — Obstacles and Opportunities in Payments

May 10th, 2018


In this hallway-style conversation (originally recorded as a video), a16z general partner Alex Rampell and Terry Angelos, SVP of Commerce Solutions …

a16z Podcast: Shifting Risk Mindsets, From Tech to Bio

May 10th, 2018


What challenges do first-time founders or tech founders encounter when building companies in the bio space, and how do they differ from traditional tech companies? In this hallway-style conversation episode of the a16z …

a16z Podcast: The Case Against Education, From Signaling to Rainbow's End

May 9th, 2018


with Bryan Caplan (@bryan_caplan), Marc Andreessen (@pmarca), and Sonal Chokshi (@smc90)

Signaling and credential inflation -- not learning -- can …

a16z Podcast: Breaking Into Bio

May 2nd, 2018


with Atul Butte (@atulbutte), Daphne Koller (@daphnekoller), and Vijay Pande (@vijaypande)

Whether you’re an academic seeking to move out of research …

a16z Podcast: Principles and Algorithms for Work and Life

April 21st, 2018


with Ray Dalio (@raydalio), Alex Rampell (@arampell), and Sonal Chokshi (@smc90)

Can one really apply the lessons of history and of the past to the present and the future, as a way to get what they want out of life? By …

a16z Podcast: On Recent Consolidation in the Healthcare Industry

April 16th, 2018


Many of the healthcare headlines lately have been about consolidation in the industry: Walmart and Humana; Aetna and CVS; Amazon, JP Morgan, and …

a16z Podcast: Players and Paths for Healthcare Startups

April 16th, 2018


The creation of each new biotechnology enables a tool, a therapy, or a diagnostic: a molecule, a protein, an app, a platform. And the process …

a16z Podcast: When (and How) Biology Becomes Engineering

April 16th, 2018


Hypothesis, test, revise -- that's science. Engineering, however, doesn't quite go that way: You have parts you know and understand (like legos), and then you use those parts to design and build something (like …

a16z Podcast: What to Know about GDPR

April 12th, 2018


with Lisa Hawke (@ldhawke) and Steven Sinofsky (@stevesi)

Given concern around data breaches, the EU Parliament finally passed GDPR (General Data …

a16z Podcast: Feedback Loops -- Company Culture, Change, and DevOps

March 28th, 2018


with Nicole Forsgren (@nicolefv), Jez Humble (@jezhumble) and Sonal Chokshi (@smc90)

From the old claim that "IT doesn't matter" and question of …

a16z Podcast: From Teaching Leadership to Being a Leader

March 26th, 2018


Few operators become VCs, and even fewer go back to leading companies... so how does these perspectives change how one leads? Obviously, it's a lot …

a16z Podcast: Improv'ing Leadership

March 23rd, 2018


Leadership is not just about management, but about passion, a bit of humor, and resilience. General partner Peter Levine and Dick Costolo …

a16z Podcast: On Morals and Meaning in Products, Business, and Life

March 21st, 2018


Focusing only on the technical, "crunchy, wonky stuff" behind policies or products sometimes misses the humanity at the center of why we're doing the …

a16z Podcast: How to Live Longer and Better

March 16th, 2018


with Kristen Fortney (@kpfortney), Jeff Kaditz (@jeffkaditz), David Sinclair (@davidasinclair), and Hanne Tidnam (@omnivorousread)

Even without a mythical fountain of youth, scientific advances have already dramatically …

a16z Podcast: The API Economy -- The Why, What, and How

March 13th, 2018


with Cristina Cordova (@cjc), Augusto Marietti (@sonicaghi), Laura Behrens Wu (@laurabehrenswu), and Sonal Chokshi (@smc90)

APIs (application programming interfaces), observe the guests in this episode of the a16z …

a16z Podcast: Containing the Monolith -- From Microservices to DevOps

March 8th, 2018


What happens when monolithic architectures are broken down into containers and microservices (or when things are broken down into smaller units, not …

a16z Podcast: Space -- the Near Frontier

March 4th, 2018


When most people think of space, they think of outer space: Mars, billionaires with rockets, and the “final frontier”. But space innovation is actually playing out right now -- in an immediate and more accessible way, …

a16z Podcast: The State of Security

February 28th, 2018


with Joel de la Garza, Stina Ehrensvärd, Niels Provos, and Martin Casado

Given the heated discussions around security and the c-word (“cyber”), it’s hard to figure out what the actual state of the industry is. And …

a16z Podcast: Creating a Category, from Pricing to Positioning

February 24th, 2018


with Martin Casado (@martin_casado), Michel Feaster (@michelfeaster) and Sonal Chokshi (@smc90)

The purpose of category creation, argue the guests in this episode of the podcast, isn't just about making a dent in the …

a16z Podcast: The Self-Flying Camera

February 22nd, 2018


with Adam Bry (@adampbry), Chris Dixon (@cdixon), and Hanne Tidnam (@omnivorousread)

Now that we've finally reached the age of the truly autonomous …

a16z Podcast: The Internet of Taste, Streaming Content to Culture

February 18th, 2018


Once upon a time it was inconceivable that a company in Silicon Valley could make content that was any good; the running joke, shares Marc …

a16z Podcast: The Business of Continual Change

February 18th, 2018


Every large company -- especially ones that have been around for a long time -- goes through multiple cycles of change. But how do you know where to …

a16z Podcast: How Technology Is Changing Investing

February 17th, 2018


As people begin to gain access to information that was previously left to only trained specialists, a new set of asset classes are being created -- and they are changing the way we think about everything from banking to …

a16z Podcast: Data, Insight, and the Customer Experience

February 13th, 2018


In 2017 The Economist declared data to be the world's most valuable resource. And yet “data insight” is one of those phrases that, while important, is now so ubiquitous it’s been numbed of meaning. So how do you …

a16z Podcast: The Evolution of Payments

February 11th, 2018


The battle between every startup and incumbent comes down to whether the startup gets distribution before the incumbent gets innovation, oft observes a16z general partner Alex Rampell. But how does this play out when …

a16z Podcast: When Is VR's iPhone Moment?

February 6th, 2018


There was a lot of hype about VR ad then it seemed to go pretty quiet. So where are we right now? Bigscreen founder Darshan Shankar and a16z general …

a16z Podcast: All about Bike Sharing

February 3rd, 2018


with Lee Kleinman (@LeeForDallas), Joshua Schank (@joshuaschank), Andrew Savage, and Hanne Tidnam (@omnivorousread)

There's a new wave of bike-sharing in town. But this wave looks a little different than previous waves …

a16z Podcast: Self-Driving Cars — Where Are We, Really?

January 31st, 2018


As cars become more like iPhones and less like just, well, cars — everything changes, from data to mapping to interfaces to security and more. How so? Where are we anyway, given all the hype around when self-driving …

a16z Podcast: Beyond CES: Connected Home Devices, Voice, and More

January 22nd, 2018


In this hallway conversation of the a16z Podcast, Benedict Evans and Steven Sinofsky discuss CES 2018 and share insight on what they took from this year's show. How much can you discern each company's "big picture" …

a16z Podcast: Mental Models for Understanding Crypto Tokens

January 22nd, 2018


This episode of the a16z Podcast goes deep on various trends in cryptocurrencies -- from mental models for understanding tokens and what may give …

a16z Podcast: Reinventing Food

January 13th, 2018


It's surprising that how (and what) we eat has actually changed very little over the ages, despite how much we’ve advanced as a species. Now, however -- driven by globalization, environmental factors, and other …

a16z Podcast: Revisiting the Gene

January 10th, 2018


The complete sequencing of the human genome is one of the most powerful examples of technology and science in action: We've gone from needing $3 …

a16z Podcast: Community and Culture, Online

January 6th, 2018


We’re so used to thinking of “community” as our friends, families, and neighbors. But what a community is, and who it is made of, has changed thanks to the internet, and without our noticing it. What happens when online …

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